Science (not) Friday - A tale of two bases
2012年12月號的Nature Chemical Biology， 刊登了讓glycobiologists振奮的兩篇competing articles， 一篇來自Harvard Medical School的Suzanne Walker lab， co-first authors: Michael Lazarus & Jiaoyang Jiang http://www.nature.com/nchembio/journal/v8/n12/abs/nchembio.1109.html 另一篇來自University of Dundee的Daan van Aalten lab co-first authors: Marianne Schimpl, Xiaowei Zheng, & Vladimir S Borodkin http://www.nature.com/nchembio/journal/v8/n12/abs/nchembio.1108.html 兩篇各自解開了human O-linked beta-N-acetyl-glucosamine tranferase (OGT)跟sbustrate peptide以及UDP-GlcNAc的ternary structure， 為OGT催化protein O-GlcNacylation的機制提供了解答 (或是更多的問題)
